BIOMARKER SCREEN FOR EFFICACY OF ONCOLYTIC VIROTHERAPY IN PATIENT-DERIVED PANCREATIC CANCER CULTURESRESEARCH IN CONTEXT

Biomarker screen for efficacy of oncolytic virotherapy in patient-derived pancreatic cancer culturesResearch in context

Summary: Background: Pancreatic ductal adenocarcinoma (PDAC) is a tumour entity with unmet medical need.To assess the therapeutic potential of oncolytic virotherapy (OVT) against PDAC, different oncolytic viruses (OVs) are currently investigated in clinical trials.However, systematic comparisons of these different OVs in terms of efficacy against P

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Applying Simulation Method in Formulation of Gluten-Free Cookies

At present time priority direction in the development of new food products its developing of technology products for special purposes.These types of products are gluten-free confectionery products, intended for people with celiac disease.Gluten-free products are in demand among consumers, it needs to expand assortment, and improvement of quality in

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To compare the efficacy of tamsulosin and tolterodine in double-J stent-related symptoms: A prospective randomized trial

Background: Stent-related symptoms affect nearly 80% of patients with indwelling ureteral stents.Alpha blockers relieve flank pain by blocking alpha-adrenergic receptors and relaxing the smooth muscles of ureter, trigone, and prostatic urethra, thus reducing bladder outlet resistance and voiding pressure, whereas mechanism of anticholinergic drugs

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Ancient Transcription Factors in the News

ABSTRACT In every cell from bacteria to mammals, NusG-like proteins bind transcribing RNA polymerase to modulate the rate of nascent RNA synthesis and to coordinate it with numerous cotranscriptional processes that ultimately determine the transcript fate.Housekeeping NusG factors regulate expression of the bulk of the genome, whereas their highly

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Edible seeds with potential anti-obesity impact: A Review

Obesity and Accessories related metabolic diseases prevalence rates have risen dramatically in the recent decades, leading to severe health issues and increased mortality rates.A pressing need is evolved for a potential solution addressing obesity undermining.Bariatric dietary supplements and alternative medicine are recently gaining growing attent

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